rs587778764
This variant is located in the XPO1 gene.
▶ClinVar annotation
About XPO1
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]
View all XPO1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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