rs59325091

This is a intron variant variant in the PGM2L1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

glycine measurement

Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)

Allele G

OR 0.04

p 6.0e-14

N 450,015

Large GWAS

multi-ancestry

About PGM2L1

Enables glucose-1,6-bisphosphate synthase activity. Predicted to be involved in glucose metabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]

View all PGM2L1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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