rs5933688
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
testosterone measurement
Venkatesh SS et al. “Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum.” Nature Genetics 57(5):1107-1118 (2025)
Allele G
OR 0.09
p 1.0e-300
N 235,096
Large GWAS
European
Pagadala MS et al. “Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men.” Nature Communications 16(1):4104 (2025)
Allele G
OR 0.05
p 1.0e-17
N 33,470
Major Consortium StudyLarge GWAS
European
estradiol measurement
Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele G
OR 0.01
p 3.0e-37
N 206,927
Large GWAS
European
Schmitz D et al. “Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density.” The Journal of Clinical Endocrinology and Metabolism 106(11):e4471-e4486 (2021)
Allele G
OR 1.12
p 7.0e-30
N 147,690
Large GWAS
European
balding measurement
Heilmann-Heimbach S et al. “Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness.” Nature Communications 8:14694 (2017)
Allele G
OR 0.10
p 5.0e-9
N 22,518
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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