rs595158
This is a intron variant variant in the VPS37C gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
rheumatoid arthritis
Eyre S et al. “High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.” Nature Genetics 44(12):1336-40 (2012)
Allele C
OR 1.09
p 3.0e-8
N 47,580
Large GWAS
European
About VPS37C
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]
View all VPS37C variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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