rs5975473
This is a regulatory region variant variant in the PLAC1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
serum creatinine amount
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.02
p 6.0e-28
N 494,370
Large GWAS
multi-ancestry
brain connectivity attribute
Sha Z et al. “Genetic architecture of the white matter connectome of the human brain.” Science Advances 9(7):eadd2870 (2023)
Allele A
OR 6.55
p 6.0e-11
N 30,810
Large GWAS
European
About PLAC1
Involved in placenta development. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
View all PLAC1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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