rs59841088

This is a downstream gene variant variant in the AJUBA gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

creativity measurement

Li WD et al. “A genome-wide association study of occupational creativity and its relations with well-being and career success.” Communications Biology 7(1):1092 (2024)

Allele A

OR 0.01

p 2.0e-9

N 219,473

Large GWAS

European

About AJUBA

Enables alpha-catenin binding activity and transcription corepressor activity. Involved in several processes, including miRNA-mediated gene silencing by inhibition of translation; negative regulation of hippo signaling; and regulation of cellular response to hypoxia. Acts upstream of or within miRNA-mediated post-transcriptional gene silencing and positive regulation of protein-containing complex assembly. Located in several cellular components, including Golgi apparatus; P-body; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all AJUBA variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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