rs60175411

This is a intron variant variant in the CSF2RB gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

eosinophil percentage of leukocytes

Vuckovic D et al. “The Polygenic and Monogenic Basis of Blood Traits and Diseases.” Cell 182(5):1214-1231.e11 (2020)

Allele A

OR 0.03

p 9.0e-20

N 408,112

Large GWAS

European

eosinophil count

Höglund J et al. “Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.” Frontiers in Immunology 13:862255 (2022)

Allele A

OR 0.04

p 2.0e-13

N 365,954

Large GWAS

European

About CSF2RB

The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]

View all CSF2RB variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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