rs602075

This variant is located in the GCNT1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gut microbiome measurement

Kurilshikov A et al. “Large-scale association analyses identify host factors influencing human gut microbiome composition.” Nature Genetics 53(2):156-165 (2021)

Allele A

OR 5.51

p 4.0e-8

N 18,340

Large GWAS

multi-ancestry

About GCNT1

This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

View all GCNT1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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