rs60627815
This variant is located in the CFHR3 gene.
▶ClinVar annotation
About CFHR3
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
View all CFHR3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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