rs6081565

This is a intron variant variant in the SLC24A3 gene.

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

dickkopf‐related protein 1 measurement

Allele A
OR 0.06
p 2.0e-27
N 47,745
Large GWAS
European

epidermal growth factor measurement

Allele A
OR 0.06
p 5.0e-21
N 47,745
Large GWAS
European

CD40 ligand measurement

Allele A
OR 0.05
p 3.0e-18
N 47,745
Large GWAS
European

About SLC24A3

Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]

View all SLC24A3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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