rs61734601

GWAS Catalog Trait Associations (11)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

health trait

Allele G
OR 0.05
p 2.0e-135
N 405,979
Large GWAS
European

mean reticulocyte volume

Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele A
OR 0.06
p 7.0e-43
N 408,112
Large GWAS
European

erythrocyte volume

Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele A
OR 0.05
p 1.0e-38
N 408,112
Large GWAS
European

lean body mass

Harris BHL et al. New role of fat-free mass in cancer risk linked with genetic predisposition. Scientific Reports 14(1):7270 (2024)
Allele A
OR 0.03
p 3.0e-33
N 337,739
Large GWAS
European

mean corpuscular hemoglobin

Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele A
OR 0.04
p 4.0e-28
N 408,112
Large GWAS
European

grip strength measurement

Allele G
OR 0.03
p 4.0e-27
N 404,112
Large GWAS
European

cysteine-rich secretory protein 2 measurement

Allele A
OR 0.05
p 5.0e-15
N 47,745
Large GWAS
European

IGF-1 measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.03
p 4.0e-12
N 353,824
Major Consortium StudyLarge GWAS
multi-ancestry

body height

Tachmazidou I et al. Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. American Journal of Human Genetics 100(6):865-884 (2017)
Allele A
OR 0.09
p 2.0e-10
N 57,129
Large GWAS
European
Allele A
OR 0.01
p 2.0e-10
N 26,828
Major Consortium StudyLarge GWAS
European

fat pad mass

Harris BHL et al. New role of fat-free mass in cancer risk linked with genetic predisposition. Scientific Reports 14(1):7270 (2024)
Allele A
OR 0.03
p 3.0e-9
N 337,196
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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