rs61742388
This variant is located in the CELA2B gene.
▶ClinVar annotation
Benign★★★☆
2 submitters2 publicationsAbout CELA2B
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2B is secreted from the pancreas as a zymogen. In other species, elastase 2B has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, Jul 2008]
View all CELA2B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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