rs61744853

This variant is located in the ZMYM6 gene.

GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body weight

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.20
p 4.0e-32
N 425,541
Major Consortium StudyLarge GWAS
European

body mass index

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.18
p 1.0e-27
N 424,231
Major Consortium StudyLarge GWAS
European
Huang J et al. Genomics and phenomics of body mass index reveals a complex disease network. Nature Communications 13(1):7973 (2022)
Allele A
OR 0.04
p 9.0e-9
N 1,122,049
Large GWAS
European

level of sperm equatorial segment protein 1 in blood

Allele C
OR 0.21
p 4.0e-14
N 47,745
Large GWAS
European

level of podocalyxin-like protein 2 in blood

Allele C
OR 0.19
p 5.0e-13
N 47,745
Large GWAS
European

cysteine-rich secretory protein 2 measurement

Allele C
OR 0.12
p 8.0e-12
N 47,745
Large GWAS
European

ClinVar annotation

Benign
1 submitter

ZMYM6-related disorder

View on ClinVar →

About ZMYM6

Predicted to enable DNA binding activity. Involved in cytoskeleton organization and regulation of cell morphogenesis. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all ZMYM6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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