rs61754487

This is a stop gained variant in the SERPINA10 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆
2 submitters2 publications

Venous thrombosis, susceptibility to

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About SERPINA10

The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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