rs61946067
This is a intron variant variant in the TAOK3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
post-traumatic stress disorder
Nievergelt CM et al. “Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.” Nature Genetics 56(5):792-808 (2024)
Allele T
OR 6.54
p 6.0e-11
N 1,222,882
Large GWAS
European
About TAOK3
The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases. [provided by RefSeq, Oct 2016]
View all TAOK3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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