rs61955089

This is a upstream gene variant variant in the SBNO1 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

neutrophil count

Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele C
OR 0.05
p 6.0e-11
N 408,112
Large GWAS
European

About SBNO1

Predicted to enable chromatin DNA binding activity and histone binding activity. Predicted to be involved in several processes, including negative regulation of neuroinflammatory response; positive regulation of neural precursor cell proliferation; and regulation of signal transduction. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all SBNO1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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