rs61981649

This variant is located in the DCAF5 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

smoking initiation

Saunders GRB et al. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 612(7941):720-724 (2022)
Allele A
OR 0.01
p 5.0e-12
N 2,669,029
Large GWAS
European

About DCAF5

Predicted to be involved in negative regulation of fatty acid biosynthetic process. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025]

View all DCAF5 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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