rs62059839
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
testosterone measurement
Harrison S et al. “Testosterone and socioeconomic position: Mendelian randomization in 306,248 men and women in UK Biobank.” Science Advances 7(31) (2021)
Allele T
OR 0.72
p 3.0e-289
N 148,248
Major Consortium StudyLarge GWAS
European
Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele T
OR 0.03
p 1.0e-23
N 230,454
Large GWAS
European
Haas CB et al. “Cross-ancestry Genome-wide Association Studies of Sex Hormone Concentrations in Pre- and Postmenopausal Women.” Endocrinology 163(4) (2022)
Allele T
OR 0.03
p 4.0e-12
N 182,648
Large GWAS
European
Pagadala MS et al. “Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men.” Nature Communications 16(1):4104 (2025)
Allele T
OR 0.14
p 2.0e-16
N 13,443
Major Consortium StudyLarge GWAS
Hispanic or Latin American
Abnormality of the skeletal system
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.01
p 2.0e-13
N 394,642
Large GWAS
European
estradiol measurement
Schmitz D et al. “Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density.” The Journal of Clinical Endocrinology and Metabolism 106(11):e4471-e4486 (2021)
Allele T
OR 1.10
p 9.0e-11
N 147,690
Large GWAS
European
sex hormone-binding globulin measurement
Pagadala MS et al. “Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men.” Nature Communications 16(1):4104 (2025)
Allele T
OR 0.25
p 5.0e-9
N 2,081
Major Consortium StudyLarge GWAS
Hispanic or Latin American
osteoarthritis, hip
Henkel C et al. “Genome-wide association meta-analysis of knee and hip osteoarthritis uncovers genetic differences between patients treated with joint replacement and patients without joint replacement.” Annals of the Rheumatic Diseases 82(3):384-392 (2023)
Allele T
OR 1.07
p 8.0e-9
N 646,831
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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