rs62075723
This variant is located in the TSPAN10 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
retinal layer thickness
Julian TH et al. “Pigmentation and Retinal Pigment Epithelium Thickness: A Study of the Phenotypic and Genotypic Relationships Between Ocular and Extraocular Pigmented Tissues.” Pigment Cell & Melanoma Research 38(4):e70038 (2025)
Allele A
OR 0.10
p 7.0e-37
N 29,550
Large GWAS
European
age at onset, Myopia
Tedja MS et al. “Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.” Nature Genetics 50(6):834-848 (2018)
Allele A
OR 0.06
p 6.0e-13
N 104,293
Meta-analysisLarge GWAS
European
About TSPAN10
Enables enzyme binding activity. Involved in establishment of protein localization to organelle. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all TSPAN10 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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