rs62098013

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

smoking initiation

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele A
OR 0.01
p 5.0e-23
N 2,669,029
Large GWAS
European
Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)
Allele A
OR 0.01
p 2.0e-14
N 931,815
Large GWAS
European

putamen volume

Satizabal CL et al. “Genetic architecture of subcortical brain structures in 38,851 individuals.” Nature Genetics 51(11):1624-1636 (2019)
Allele A
OR 9.11
p 8.0e-20
N 37,571
Large GWAS
multi-ancestry

multisite chronic pain

Johnston KJA et al. “Genome-wide association study of multisite chronic pain in UK Biobank.” Plos Genetics 15(6):e1008164 (2019)
Allele G
OR 0.02
p 4.0e-11
N 387,649
Major Consortium StudyLarge GWAS
European

creativity measurement

Li WD et al. “A genome-wide association study of occupational creativity and its relations with well-being and career success.” Communications Biology 7(1):1092 (2024)
Allele G
OR 0.01
p 4.0e-10
N 219,473
Large GWAS
European

smoking behavior trait

Wootton RE et al. “Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.” Psychological Medicine 50(14):2435-2443 (2020)
Allele G
OR 0.01
p 4.0e-9
N 462,690
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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