rs62252355
This is a intron variant variant in the FRMD4B gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
retinal layer thickness
Currant H et al. “Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.” Plos Genetics 17(5):e1009497 (2021)
Allele C
OR 0.37
p 2.0e-16
N 31,434
Major Consortium StudyLarge GWAS
European
retinal nerve fibre layer thickness
Currant H et al. “Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.” Plos Genetics 17(5):e1009497 (2021)
Allele C
OR 0.37
p 2.0e-16
N 31,434
Major Consortium StudyLarge GWAS
European
About FRMD4B
This gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014]
View all FRMD4B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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