rs62262093

This is a intron variant variant in the MON1A gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

visceral adipose tissue quantity

Karlsson T et al. “Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.” Nature Medicine 25(9):1390-1395 (2019)

Allele T

OR 0.03

p 1.0e-33

N 325,153

Large GWAS

European

free cholesterol to total lipids in small HDL percentage

Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)

Allele C

OR 0.02

p 2.0e-24

N 450,015

Large GWAS

multi-ancestry

About MON1A

Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in protein secretion. Predicted to act upstream of or within establishment of localization in cell; intracellular iron ion homeostasis; and protein transport. Part of Mon1-Ccz1 complex. [provided by Alliance of Genome Resources, Jul 2025]

View all MON1A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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