rs6414946
This is a coding sequence variant variant in the TMEM161B-DT gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
educational attainment
Okbay A et al. “Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.” Nature Genetics 54(4):437-449 (2022)
Allele A
OR 0.01
p 2.0e-43
N 3,037,499
Large GWAS
European
polyunsaturated fatty acids to total fatty acids percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 4.0e-12
N 450,015
Large GWAS
multi-ancestry
smoking initiation
Erzurumluoglu AM et al. “Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.” Molecular Psychiatry 25(10):2392-2409 (2020)
Allele C
OR 0.01
p 5.0e-10
N 346,813
Meta-analysisLarge GWAS
multi-ancestry
About TMEM161B-DT
Predicted to be a structural constituent of ribosome. Predicted to be located in ribosome. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM161B-DT variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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