rs6441286
This is a upstream gene variant variant in the IL12A-AS1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
biliary liver cirrhosis
Hirschfield GM et al. “Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.” The New England Journal of Medicine 360(24):2544-55 (2009)
Allele G
OR 1.54
p 2.0e-14
N 2,012
Large GWAS
European
Liu X et al. “Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis.” Nature Genetics 42(8):658-60 (2010)
Allele G
OR 1.44
p 8.0e-12
N 1,398
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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