rs6444175

This is a downstream gene variant variant in the ADIPOQ-AS1 gene.

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Research that mentions this SNP (1)

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Genetic polymorphisms in obesity‐related genes and endometrial cancer risk
AssociationN=2,960Xiaoli Chen et al.(2012)· Cancer

This case-control study of 1,028 endometrial cancer cases and 1,932 controls from Shanghai evaluated 87 SNPs in five obesity-related genes (ADIPOQ, ADIPOR1, ADIPOR2, LEP, LEPR). Three ADIPOQ SNPs (rs3774262 OR=0.68, rs1063539 OR=0.66, rs12629945) and one LEP SNP (rs2071045 OR=0.70) were significantly associated with reduced endometrial cancer risk. The ADIPOQ variants were also associated with lower body weight, waist circumference, and BMI in controls, suggesting a potential mechanism through obesity.

Traits studied:Body mass indexEndometrial cancerHip circumferenceObesityWaist circumference
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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