rs6445424
This is a intron variant variant in the ADAMTS9-AS2 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
type 2 diabetes mellitus
Huerta-Chagoya A et al. “Rare variant analyses in 51,256 type 2 diabetes cases and 370,487 controls reveal the pathogenicity spectrum of monogenic diabetes genes.” Nature Genetics 56(11):2370-2379 (2024)
Allele C
OR 0.07
p 4.0e-14
N 421,743
Large GWAS
multi-ancestry
leukocyte quantity
Vuckovic D et al. “The Polygenic and Monogenic Basis of Blood Traits and Diseases.” Cell 182(5):1214-1231.e11 (2020)
Allele A
OR 0.02
p 9.0e-11
N 408,112
Large GWAS
European
About ADAMTS9-AS2
Implicated in diabetic retinopathy. [provided by Alliance of Genome Resources, Jul 2025]
View all ADAMTS9-AS2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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