rs6503451
This is a intron variant variant in the MAPT-AS1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
left ventricular mass index
Khurshid S et al. “Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass.” Nature Communications 14(1):1558 (2023)
Allele T
OR 0.52
p 1.0e-10
N 43,230
Large GWAS
multi-ancestry
left ventricular mass
Khurshid S et al. “Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass.” Nature Communications 14(1):1558 (2023)
Allele T
OR 1.01
p 1.0e-9
N 43,230
Large GWAS
multi-ancestry
About MAPT-AS1
Involved in regulatory ncRNA-mediated gene silencing. Implicated in Parkinson's disease. [provided by Alliance of Genome Resources, Jul 2025]
View all MAPT-AS1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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