rs6549455
This variant is located in the RYBP gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
BMI-adjusted waist circumference
Graff M et al. “Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.” Plos Genetics 13(4):e1006528 (2017)
Allele G
OR 0.03
p 9.0e-9
N 122,328
Meta-analysisLarge GWAS
multi-ancestry
About RYBP
Enables nucleic acid binding activity. Involved in chromatin remodeling; positive regulation of apoptotic process; and regulation of primary metabolic process. Located in nucleoplasm. Part of PcG protein complex. [provided by Alliance of Genome Resources, Jul 2025]
View all RYBP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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