rs6575005
This is a intron variant variant in the NOVA1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
sleep duration trait
Scammell BH et al. “Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration.” Human Molecular Genetics 32(18):2797-2807 (2023)
Allele T
OR 0.02
p 2.0e-9
N 483,235
Large GWAS
multi-ancestry
Dashti HS et al. “Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.” Nature Communications 10(1):1100 (2019)
Allele T
OR 0.86
p 4.0e-9
N 446,118
Large GWAS
European
About NOVA1
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
View all NOVA1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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