rs6624142

This is a coding sequence variant variant in the ZC3H12B gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

alopecia

Hagenaars SP et al. “Genetic prediction of male pattern baldness.” Plos Genetics 13(2):e1006594 (2017)

Allele C

OR —

β 0.079

p 4.0e-13

N 52,874

Large GWAS

European

About ZC3H12B

The protein encoded by this gene belongs to a family of CCCH-type zinc finger proteins that are involved in the proinflammatory activation of macrophages. The exact function of this family member is unknown, but it is thought to function as a ribonuclease. [provided by RefSeq, May 2010]

View all ZC3H12B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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