rs6671200

This is a upstream gene variant variant in the TLCD4-RWDD3 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

fatty acid amount

Wu JH et al. “Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.” Circulation. Cardiovascular Genetics 6(2):171-83 (2013)

Allele A

OR 0.25

p 2.0e-15

N 8,961

Major Consortium StudyLarge GWAS

European

About TLCD4-RWDD3

This locus represents naturally occurring read-through transcription between the neighboring TMEM56 (transmembrane protein 56) and RWDD3 (RWD domain containing 3) genes on chromosome 1. The read-through transcript encodes a protein that shares sequence identity with the upstream gene product, but it contains a distinct C-terminus due to frameshifts versus the downstream gene coding sequence. [provided by RefSeq, Dec 2010]

View all TLCD4-RWDD3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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