rs66833742
This is a regulatory region variant variant in the ZBTB7A gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
COVID-19
Pairo-Castineira E et al. “GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.” Nature 617(7962):764-768 (2023)
Allele T
OR 0.93
p 2.0e-10
N 2,974,917
Meta-analysisLarge GWAS
multi-ancestry
Diz-de Almeida S et al. “Novel risk loci for COVID-19 hospitalization among admixed American populations.” Elife 13 (2024)
Allele T
OR 0.94
p 3.0e-8
N 73,303
Large GWAS
multi-ancestry
About ZBTB7A
Enables several functions, including SMAD binding activity; nuclear androgen receptor binding activity; and transcription corepressor binding activity. Involved in several processes, including erythrocyte maturation; negative regulation of signal transduction; and regulation of nucleobase-containing compound metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all ZBTB7A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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