rs6726821
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bone tissue density, lean body mass
Medina-Gomez C et al. “Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.” Nature Communications 8(1):121 (2017)
Allele G
OR —
p 4.0e-8
N 10,414
Meta-analysisLarge GWAS
European, NR
bone tissue density
Medina-Gomez C et al. “Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.” Nature Communications 8(1):121 (2017)
Allele T
OR —
β 0.077
p 3.0e-8
N 10,414
Meta-analysisLarge GWAS
European, NR
Kemp JP et al. “Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.” Plos Genetics 10(6):e1004423 (2014)
Allele T
OR 0.08
p 1.0e-8
N 9,416
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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