rs6728752

This is a intron variant variant in the GFPT1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

spinal stenosis

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele A

OR 0.09

p 9.0e-10

N 633,513

Large GWAS

multi-ancestry

About GFPT1

This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008]

View all GFPT1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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