rs6782029

This variant is located in the VGLL4 gene.

Research that mentions this SNP (1)

Genetic variants associated with disordered eating
AssociationN=2,564Tracey D. Wade et al.(2013)· International Journal of Eating Disorders

This GWAS examined genetic variants associated with disordered eating in 2,564 female twins using four eating disorder phenotypes (anorexia nervosa spectrum, bulimia nervosa spectrum, purging via substances, and disordered eating behaviors). Six regions reached suggestive significance (p<5×10⁻⁷), implicating CLEC5A, LOC136242, TSHZ1, and SYTL5 for anorexia nervosa spectrum; NT5C1B for bulimia nervosa spectrum; and ATP8A2 for disordered eating behaviors. No variants reached genome-wide significance at p<10⁻⁸.

Traits studied:Anorexia nervosa spectrumBulimia nervosa spectrumDisordered eating behaviorsEating disordersPurging via substances

About VGLL4

Predicted to enable transcription coactivator binding activity. Involved in negative regulation of Wnt signaling pathway; negative regulation of cell growth; and negative regulation of hippo signaling. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all VGLL4 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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