rs6784820

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

household income

Hill WD et al. “Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.” Nature Communications 10(1):5741 (2019)
Allele G
OR 0.02
p 1.0e-13
N 505,541
Large GWAS
European, NR
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Research that mentions this SNP (1)

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Investigation of the association between Rho/Rho-kinase gene polymorphisms and systemic sclerosis
AssociationN=641Yavuz Pehlivan et al.(2016)· Rheumatology International

A multicenter case-control study investigating the association between Rho/Rho-kinase gene polymorphisms and systemic sclerosis (SSc) in a Turkish population. The study of 339 SSc patients and 302 healthy controls identified significant associations with rs35996865 (ROCK1, p=0.0005), rs10178332 (ROCK2, p<0.001), rs2177268 (RhoA, p<0.001), and rs11102522 and rs11538960 (RhoC, p<0.001), suggesting these SNPs are important genetic risk factors for SSc development.

Traits studied:Cardiac involvementGastrointestinal system involvementPulmonary arterial hypertensionPulmonary involvementRaynaud's phenomenonRenal involvementSystemic sclerosis
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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