rs67886110
This variant is located in the MED12L gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
blood immunoglobulin amount
Butler-Laporte G et al. “Genetic Determinants of Antibody-Mediated Immune Responses to Infectious Diseases Agents: A Genome-Wide and HLA Association Study.” Open Forum Infectious Diseases 7(11):ofaa450 (2020)
Allele G
OR 0.09
p 2.0e-8
N 7,972
Large GWAS
European
About MED12L
The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010]
View all MED12L variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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