rs6793295

This is a protein-altering variant in the LRRC34 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

interstitial lung disease

Fingerlin TE et al. “Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.” Nature Genetics 45(6):613-20 (2013)

Allele C

OR 1.30

p 8.0e-13

N 5,844

Large GWAS

European

thyroid carcinoma

Gudmundsson J et al. “A genome-wide association study yields five novel thyroid cancer risk loci.” Nature Communications 8:14517 (2017)

Allele T

OR 1.23

p 3.0e-8

N 290,551

Large GWAS

European

About LRRC34

Predicted to be involved in cell differentiation. Predicted to act upstream of or within gene expression and telomere maintenance. Predicted to be located in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Jul 2025]

View all LRRC34 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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