rs67991850

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brain attribute

van der Meer D et al. The genetic architecture of human cortical folding. Science Advances 7(51):eabj9446 (2021)
Allele T
OR 8.06
p 8.0e-16
N 33,748
Large GWAS
European

radius bone mineral density

Chesi A et al. A Genomewide Association Study Identifies Two Sex-Specific Loci, at SPTB and IZUMO3, Influencing Pediatric Bone Mineral Density at Multiple Skeletal Sites. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research 32(6):1274-1281 (2017)
Allele T
OR 0.35
p 9.0e-12
N 933
Small GWAS
European

bone tissue density

Mitchell JA et al. Multidimensional Bone Density Phenotyping Reveals New Insights Into Genetic Regulation of the Pediatric Skeleton. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research 33(5):812-821 (2018)
Allele C
OR 0.24
p 3.0e-11
N 1,399
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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