rs681343
This variant is located in the FUT2 gene.
▶GWAS Catalog Trait Associations (45)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (45)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of chymotrypsin-like elastase family member 3A in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.17
p 2.0e-261
N 47,745
Large GWAS
European
level of serine protease inhibitor Kazal-type 5 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.16
p 3.0e-248
N 47,745
Large GWAS
European
level of organic solute transporter subunit beta in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.17
p 5.0e-209
N 47,745
Large GWAS
European
level of tetraspanin-8 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.14
p 1.0e-197
N 47,745
Large GWAS
European
enteropeptidase measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.16
p 2.0e-194
N 47,745
Large GWAS
European
milk amount
Ambalavanan A et al. “Human milk oligosaccharides are associated with maternal genetics and respiratory health of human milk-fed children.” Nature Communications 15(1):7735 (2024)
Allele T
OR 28.65
p 2.0e-180
N 980
Small GWAS
multi-ancestry
level of carcinoembryonic antigen-related cell adhesion molecule 20 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.14
p 2.0e-128
N 47,745
Large GWAS
European
stromelysin-2 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.12
p 1.0e-116
N 47,745
Large GWAS
European
interleukin-22 receptor subunit alpha-1 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.14
p 1.0e-114
N 47,745
Large GWAS
European
epithelial discoidin domain-containing receptor 1 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.11
p 5.0e-108
N 47,745
Large GWAS
European
▶ClinVar annotation
About FUT2
This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. The encoded protein is important for the final step in the soluble ABO blood group antigen synthesis pathway. It is also involved in cell-cell interaction, cell surface expression, and cell proliferation. Mutations in this gene are a cause of the H-Bombay blood group where red blood cells lack the H antigen. [provided by RefSeq, May 2022]
View all FUT2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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