rs6821144

This is a intron variant variant in the CDKL2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Testicular Germ Cell Tumor

Litchfield K et al. “Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor.” Nature Genetics 49(7):1133-1140 (2017)

Allele G

OR 1.22

p 2.0e-11

N 24,573

Large GWAS

European

About CDKL2

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]

View all CDKL2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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