rs6854541

This variant is located in the SLC10A7 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

smoking initiation

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)

Allele G

OR 0.01

p 1.0e-17

N 3,382,012

Large GWAS

European, East Asian, Hispanic or Latin American, African unspecified

About SLC10A7

Predicted to enable symporter activity. Involved in bone development; heparin proteoglycan biosynthetic process; and intracellular calcium ion homeostasis. Located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all SLC10A7 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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