rs687339

GWAS Catalog Trait Associations (71)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

bilirubin measurement

Allele T
OR 0.05
p 1.0e-138
N 394,642
Large GWAS
European

di-N-acetylchitobiase measurement

Allele T
OR 0.13
p 9.0e-99
N 47,745
Large GWAS
European

triglycerides in IDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.04
p 3.0e-72
N 450,015
Large GWAS
multi-ancestry
Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.05
p 2.0e-22
N 136,016
Large GWAS
multi-ancestry

IGF-1 measurement

Allele T
OR 0.03
p 1.0e-56
N 394,642
Large GWAS
European

acid sphingomyelinase-like phosphodiesterase 3a measurement

Allele T
OR 0.08
p 2.0e-55
N 47,745
Large GWAS
European

alkaline phosphatase measurement

Allele C
OR 0.00
p 1.0e-44
N 437,438
Large GWAS
European
Allele C
OR 0.03
p 2.0e-37
N 394,642
Large GWAS
European
Allele C
OR 10.60
p 2.0e-26
N 390,964
Large GWAS
multi-ancestry

level of contactin-3 in blood serum

Allele T
OR 0.08
p 3.0e-41
N 47,745
Large GWAS
European

testosterone measurement

Allele T
OR 0.04
p 4.0e-39
N 188,507
Large GWAS
European

phospholipids in very small VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.03
p 8.0e-39
N 450,015
Large GWAS
multi-ancestry

epididymis-specific alpha-mannosidase measurement

Allele T
OR 0.05
p 4.0e-35
N 47,745
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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