rs691638
This variant is located in the TMEM45B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GM3 ganglioside measurement
Cadby G et al. “Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease.” Nature Communications 13(1):3124 (2022)
Allele C
OR 0.13
p 5.0e-9
N 4,492
Large GWAS
European
About TMEM45B
Predicted to be involved in innate immune response. Predicted to be located in Golgi apparatus; endosome membrane; and lysosomal membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM45B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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