rs6923737
This variant is located in the BTBD9 gene.
▶Research that mentions this SNP (1)
▶TheBTBD9gene may be associated with antipsychotic‐induced restless legs syndrome in schizophreniaAssociationN=190Seung‐Gul Kang et al.(2013)· Human Psychopharmacology: Clinical and Experimental
A case-control study of 190 Korean schizophrenic patients examining the association between BTBD9 gene polymorphisms and antipsychotic-induced restless legs syndrome (RLS). The rs9357271 T allele showed significant association with RLS symptoms (p=0.004, OR=2.36), with dominant (p=0.001, OR=2.98) and heterozygous models (p=0.001, OR=3.19) also significant. The A-T haplotype (rs3923809-rs9357271) was more frequent in RLS patients (0.122 vs 0.041, p=0.007).
About BTBD9
This locus encodes a BTB/POZ domain-containing protein. This domain is known to be involved in protein-protein interactions. Polymorphisms at this locus have been reported to be associated with susceptibility to Restless Legs Syndrome and may also be associated with Tourette Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011]
View all BTBD9 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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