rs6949391
This variant is located in the FAM185A gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
diverticular disease
Wu Y et al. “150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.” Cell Genomics 3(7):100326 (2023)
Allele T
OR 0.06
p 5.0e-26
N 454,768
Large GWAS
European
Maguire LH et al. “Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease.” Nature Genetics 50(10):1359-1365 (2018)
Allele T
OR —
β 0.004
p 4.0e-14
N 409,728
Large GWAS
European
insomnia
Watanabe K et al. “Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.” Nature Genetics 54(8):1125-1132 (2022)
Allele T
OR 0.01
p 4.0e-9
N 2,365,010
Meta-analysisLarge GWAS
European
About FAM185A
Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
View all FAM185A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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