rs6973667
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bone fracture
Nethander M et al. “An atlas of genetic determinants of forearm fracture.” Nature Genetics 55(11):1820-1830 (2023)
Allele A
OR 1.05
p 2.0e-17
N 1,020,094
Large GWAS
European
bone tissue density
Qian 钱雨 Y et al. “Genome-wide Association Studies of over 30,000 Samples with Bone Mineral Density at Multiple Skeletal Sites and Its Clinical Relevance.” Genomics, Proteomics & Bioinformatics 23(5) (2025)
Allele G
OR 0.05
p 3.0e-9
N 31,986
Large GWAS
European
Surakka I et al. “MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.” Nature Communications 11(1):4093 (2020)
Allele G
OR 0.07
p 6.0e-9
N 21,907
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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