rs7084817
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
sodium channel subunit beta-2 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.45
p 1.0e-53
N 10,708
Large GWAS
European
protein measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.36
p 4.0e-38
N 10,708
Large GWAS
European
cadherin-related family member 3 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.26
p 2.0e-18
N 10,708
Large GWAS
European
level of protein kinase C-binding protein NELL2 in blood serum
Kuliesius J et al. “Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.” Communications Biology 8(1):1300 (2025)
Allele G
OR 1.29
p 9.0e-17
N 200
Small GWAS
European
single Ig IL-1-related receptor measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.21
p 3.0e-12
N 10,708
Large GWAS
European
▶Research that mentions this SNP (1)
▶Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathyAssociationN=1,711Savage DA et al.(2008)· Diabetologia
Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy
AssociationN=1,711Savage DA et al.(2008)· Diabetologia
This case-control study investigated 1,111 non-synonymous SNPs in 1,711 type 1 diabetic individuals (894 cases with diabetic nephropathy, 817 controls) to assess genetic susceptibility to diabetic nephropathy. After correction for multiple testing, no SNPs demonstrated significant associations with diabetic nephropathy, including in subgroup analyses by ESRD status or diabetes duration.
Traits studied:Diabetic nephropathyEnd-stage renal disease (ESRD)
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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