rs7121112

This is a intron variant variant in the C11orf65 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

erythrocyte volume

Vuckovic D et al. “The Polygenic and Monogenic Basis of Blood Traits and Diseases.” Cell 182(5):1214-1231.e11 (2020)

Allele C

OR 0.03

p 3.0e-41

N 408,112

Large GWAS

European

renal carcinoma

Purdue MP et al. “Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions.” Nature Genetics 56(5):809-818 (2024)

Allele C

OR 1.07

p 2.0e-10

N 864,690

Large GWAS

multi-ancestry

About C11orf65

Predicted to be involved in negative regulation of mitochondrial fission and negative regulation of protein targeting to mitochondrion. Predicted to be located in cytosol and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all C11orf65 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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