rs7129440

This is a intron variant variant in the METTL15 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

diet measurement

Merino J et al. “Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits.” Nature Human Behaviour 6(1):155-163 (2022)

Allele A

OR —

p 6.0e-12

N 282,271

Large GWAS

European

About METTL15

Enables rRNA (cytosine-N4-)-methyltransferase activity. Involved in rRNA base methylation. Is active in mitochondrial matrix. [provided by Alliance of Genome Resources, Jul 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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